A major advantage of being members of the Society for Research on Adolescence is that we have access to a vast amount of evidence about the social, emotional, and cognitive development of children and adolescents. In addition, we have learned a great deal about the risk factors for dysfunctional development in those areas. Using this information, many educational programs and clinical treatments have been developed that have shown significant pre- to post-treatment decreases in adolescents’ drinking, smoking, and risky sexual behaviors. Unfortunately, many studies that have followed participants over longer periods (6 months to several years) have found that the small to moderate effect sizes tend to dissipate. Perhaps we are missing a piece of the puzzle. Why do these effects often disappear in the longer run? I would suggest that what might be missing is something physiological that interferes with the retrieval of information learned in these programs. Recent research shows that at high levels of emotional arousal, cognitive functioning is disrupted, often inaccessible, resulting in a panic-ridden reversion to over-learned, habitual, and sometimes maladaptive behaviors. In addition, previous attachment research has helped us to understand how these over-learned, habitual, and sometimes maladaptive behaviors develop. I suggest here that we attend to coupling these two lines of research – attachment and physiological arousal – in order to improve the efficacy of our educational and clinical interventions.